Multi-scale Mechanics Analysis of Bone Remodeling in Normal vs. Osteoporotic Trabecular Bone

Georgia Tech Research Corporation, Atlanta GA

Investigators

Abstract

0085137 We will address remodeling in trabecular bone from a mechanical viewpoint. In order to understand how mechanical factors contribute to this process we will predict local stress and strain fields at the cellular level where bone remodeling takes place. In particular we are interested in differences between healthy and osteoporotic bones. By knowing local fields in these two types of bone, under the same external loads, we hope to determine relations between mechanical load and bone remodeling in healthy and osteoporotic bone. Our analysis will account for the hierarchical nature of bone and will involve both theory and experiments.