The HIV Reservoir

$583,857ZIAFY2025AINIH

National Institute Of Allergy And Infectious Diseases

Investigators

Linked publications & trials

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Abstract

In this project we aim to understand the mechanisms by which the HIV reservoir is established in resting and activated T cells. The current work involves identifying the molecular mechanisms how HIV infects resting primary CD4 T cells and integrates into the genome. Specific attention is paid to the role of VPR in disabling host proteins.

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