Multiplexed Nucleic Acid Self-Test for Reproducible and Sensitive HIV Detection

Vivid Bioinnovations, Pbc, San Francisco CA

Investigators

Abstract

Rapid Diagnostic Assays for Self-Monitoring of Acute or Rebound HIV-Infection: This program aims to support early-stage diagnostic technologies as platforms for developing simple, low-cost, rapid diagnostic assays to enable individuals to directly detect HIV-1 during the earliest stages of initial infection or to monitor viral suppression in chronic treated infection times when antibody responses are not an accurate surrogate for viral load. This contract aims to develop a droplet digital LAMP method to detect and quantify HIV in blood, synthesizing the necessary primers, probes, and spike-in nucleic acids.