Metabolic Studies of Mouse Models of Obesity and Diabetes

$867,659ZICFY2025DKNIH

National Institute Of Diabetes And Digestive And Kidney Diseases

Investigators

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Abstract

The following projects have been supported by Mouse Metabolism Core in FY 2025: 1. DK075021 Role of G protein-coupled receptors in regulating glucose and energy homeostasis Principal Investigator: Hans Jurgen Wess (LBC, NIDDK) 2. DK043313 Role of the Gnas Gene in Metabolic Regulation Principal Investigator: Lee S. Weinstein (MDB, NIDDK) 3. DK043315 Role of Gs-alpha in central regulation of energy and glucose metabolism Principal Investigator: Lee S. Weinstein (MDB, NIDDK) 4. DK043318 Role of Gs-alpha in pancreatic islet cell growth and function Principal Investigator: Lee S. Weinstein (MDB, NIDDK) 5. DK075056 Role of Gq/11-alpha in metabolic regulation Principal Investigator: Lee S. Weinstein (MDB, NIDDK) 6. DK031117 Development of drugs acting at adenosine receptors Principal Investigator: Kenneth A Jacobson (LBC, NIDDK) 7. DK075057 DEOB Physiology and pharmacology of BRS-3 (Bombesin Receptor Subtype-3) Principal Investigator: Marc L. Reitman (DEOB, NIDDK) 8. DK075063 What can body temperature tell us about energy homeostasis? Principal Investigator: Marc L. Reitman (DEOB, NIDDK) 9. DK075064 Role of brown adipose tissue (BAT) in energy balance Principal Investigator: Marc L. Reitman (DEOB, NIDDK) 10. DK075017 Epigenomic regulation of adipogenesis and adipose expansion Principal Investigator: Kai Ge (LERB, NIDDK) 11. DK075013 Nonalcoholic Steatohepatitis: Natural History, Pathogenesis and Therapy Principal Investigator: Yaron Rotman (LDB, NIDDK) 12. DK075042 The role of PKD proteins in regulating tubular morphology Principal Investigator: Gregory G. Germino (KDB, MIDDK) 13. DK054508 Regulation of hepatic and systemic immune responses Principal Investigator: Barbara Rehermann (LDB, NIDDK) 14. DK055106 Transforming growth factor - beta superfamily signaling in diabetes and obesity Principal Investigator: Sushil Rane (DEOB, NIDDK) 15. DK055107 Cell cycle regulators in diabetes and obesity Principal Investigator: Sushil Rane (DEOB, NIDDK) 16. HD001010 Mechanism and Regulation of Eukaryotic Protein Synthesis Principal Investigator: Thomas E. Dever (Section on Protein Biosynthesis, NICHD) 17. 19. BC005708 Xenobiotic receptors Principal Investigator: Frank J Gonzalez (LM, NCI)

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