Core--Osteotoxicology

$228,547P30FY2002ESNIH

University Of Rochester, Rochester NY

Investigators

Linked publications & trials

Paper 39711879 Paper 39682757 Paper 39621551 Paper 39612168 Paper 39591312 Paper 39560627 Paper 39543686 Paper 39499804 Paper 39478773 Paper 39323894 Paper 39317269 Paper 39281073 Paper 39278320 Paper 39276392 Paper 39230330 Paper 39193654 Paper 39190315 Paper 39149382 Paper 39148650 Paper 39127830 Paper 39095385 Paper 39071258 Paper 39048109 Paper 39038774 Paper 39034020 Paper 39018010 Paper 39002649 Paper 38983462 Paper 38946256 Paper 38942277 Paper 38941336 Paper 38901696 Paper 38873034 Paper 38851377 Paper 38546836 Paper 38411188 Paper 38357551 Paper 38290163 Paper 38282602 Paper 38229397 Paper 38214376 Paper 38095662 Paper 38084407 Paper 38081392 Paper 38038158 Paper 37966803 Paper 37939567 Paper 37903065 Paper 37870488 Paper 37858899 Paper 37836385 Paper 37832849 Paper 37829111 Paper 37777345 Paper 37658449 Paper 37642674 Paper 37639638 Paper 37624591 Paper 37549967 Paper 37506868 Paper 37477622 Paper 37470773 Paper 37392210 Paper 37369370 Paper 37334869 Paper 37237442 Paper 37161057 Paper 37124477 Paper 36881561 Paper 36813173 Paper 36759019 Paper 36621469 Paper 36596874 Paper 36577279 Paper 36541220 Paper 36529309 Paper 36509212 Paper 36407672 Paper 36318273 Paper 36291185 Paper 36214654 Paper 36200918 Paper 36181892 Paper 36068185 Paper 36028225 Paper 35945578 Paper 35901086 Paper 35868427 Paper 35817128 Paper 35697719 Paper 35661784 Paper 35654246 Paper 35643326 Paper 35616999 Paper 35543423 Paper 35444027 Paper 35400784 Paper 35343813 Paper 35264781 Paper 35233972

Abstract

The Osteotoxicology Research Core is a new addition to the EHSC. The goal of this Core is to generate basic information on how environmental, occupational, and foreign agents adversely affect skeletal tissues, and how these effects impact quality of life. This proposed Core has five investigators, all of whom are new to the EHSC. The five major projects within the Core surround the themes of: 1) toxicology of the adult skeleton; 2) toxicology of the developing skeleton; and, 3) toxicological effects of metals in oral biology. Specifically, these projects include the following: 1) the effects of lead on bone remodeling in vitro (Dr. Puzas, with Drs. O?Keefe, Hicks, and Pounds); 2) animal models of lead-induced osteoporosis (Drs. Puzas and Pounds, with Dr. Cory-Slechta); 3) the effect of foreign wear debris in osteolysis around implants (Dr. O?Keefe, with Drs. Puzas and Hicks); 4) effect of lead on growth plate chondrocytes (Dr. Hicks, with Drs. Puzas, O?Keefe, and Cory-Slechta); 5) environmental influences of dental caries (Dr. Bowen, with Drs. Puzas, Pounds, Clarkson).

View original record on NIH RePORTER →