NRG Oncology NCORP Research Base

Nrg Oncology Foundation, Inc., Philadelphia PA

Investigators

Linked publications & trials

Abstract

The objective of this proposal is to maintain the NRG Oncology National Community Oncology Research Program (NCORP) research base. NRG NCORP, comprised of a multi-disciplinary team of investigators and patient advocates, is poised to carry out the following aims: 1) designing and conducting cancer control research to mitigate cancer-related symptoms and improve quality of life; 2) developing clinical trials to improve the effectiveness of cancer prevention interventions and trials to evaluate biomarkers of risk of malignancies; 3) improving cancer care delivery through multidisciplinary interventions throughout the continuum of cancer from diagnosis, treatment and survivorship to palliative care; 4) integrating health care access research questions into cancer prevention, control, cancer care delivery and therapeutic clinical trials; 5) selecting and embedding patient reported outcomes in NCORP and NRG therapeutic trials; 6) mentoring and training for the next generation of clinical cancer investigators. To meet these goals, the group engages NCORP site members by holding regular in person and virtual meetings; encouraging committee membership; including them as reviewers during NCORP concept development and/or reviews: conducting concept site feasibility surveys: and appointing NCORP site members as NCORP community co-chairs on NRG trials and NCI committees. To operationalize our goals NRG NCORP participates fully in NRG Oncology leadership to determine the scientific direction and prioritization of the NRG NCORP activities and resources. With the NRG Statistical and Data Management Center (SDMC), this team will provide efficient, methodologically up-to-date trial design with a focus on NCORP specific needs such as patient- reported repeated longitudinal assessments and cluster-randomized designs. NRG NCORP will provide study monitoring, reporting, and analysis; provide comprehensive data management quality control and quality assurance programs to ensure high data integrity and timely data for analysis; leverage cutting edge information technology emphasizing security, timeliness, and efficiency of data collection and management; deliver RT credentialing and quality assurance; and offer education and training for institutional Research Associates, Study Chairs, local Principal Investigators and others involved in the NRG NCORP research agenda. Further, to accomplish these aims NRG NCORP will engage fully with NCORP community physicians and patient advocates as well as the NCI and other NCI-sponsored entities (cooperative groups, cancer centers) to collaborate across the NCTN to improve cancer prevention and control, cancer care and outcomes, and quality of life for patients affected by cancer.