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Mentoring Early Career Researchers in Patient-Oriented Research in Kidney Disease

$105,966K26FY2025DKNIH

Children'S Hosp Of Philadelphia, Philadelphia PA

Investigators

Linked publications & trials

Abstract

There is a critical need to train the next generation of scientists and expand the workforce to improve care for children with kidney disease. Effective mentoring at early career stages is fundamental to successful career advancement in biomedical research. The candidate for this NIDDK Investigator Award to Support Mentoring of Early Career Researchers is Michelle Denburg, MD, MSCE. Dr. Denburg is an Associate Professor of Pediatrics and Epidemiology at the University of Pennsylvania Perelman School of Medicine (PSOM) and is a practicing pediatric nephrologist at the Children's Hospital of Philadelphia (CHOP). PSOM and CHOP offer an ideal setting for collaboration, mentorship, didactic training, and opportunities in patient-oriented research, and Dr. Denburg’s leadership roles and responsibilities are highly synergistic with the goals of this award. Dr. Denburg’s multidisciplinary research program is focused on managing complications of and improving health outcomes in childhood kidney diseases, including chronic kidney disease (CKD), glomerular disease, and kidney stone disease, with a particular interest in bone health and altered mineral and vitamin D metabolism. Her research includes analyses of large electronic health record databases, ancillary studies to existing NIDDK-funded prospective cohort studies, and observational, translational, and interventional patient-oriented studies. Dr. Denburg has a long-standing and demonstrated commitment to research and career mentoring. Over the past 13 years, Dr. Denburg has mentored over 40 individuals across multiple disciplines, institutions, and career stages. The majority of these individuals have continued their careers in academic medicine and remain engaged in research. With this award, Dr. Denburg aims to continue to provide effective mentoring in the conduct of rigorous patient-oriented pediatric research to early career researchers, with a focus on recruiting and mentoring individuals pursuing patient-oriented research in kidney disease. Dr. Denburg will pursue additional evidence-based training programs designed to reinforce and enhance skills in mentoring of early career researchers and fostering their transition to independence. She will develop sustainable mentoring approaches that contribute to the wider mentoring environment and expand training infrastructure and resources to promote research in kidney disease at CHOP and Penn. Dr. Denburg’s long-term career goals are to conduct interdisciplinary clinical and translational research that improves the health and well-being of children and young adults with kidney disease and to catalyze the careers of trainees to become independent investigators in kidney disease research. Support from the K26 award will help sustain her active mentoring program and expand her mentoring capacity to enable her to take on 1-2 new postdoctoral mentees and at least one predoctoral summer student each year of the proposed award.

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