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Predoctoral Training in Quantitative Cell & Molecular Biology

$367,928T32FY2025GMNIH

Colorado State University, Fort Collins CO

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Abstract

The Quantitative Cell and Molecular Biology (qCMB) Training Program provides comprehensive and flexible training in quantitative approaches in order to facilitate cross-disciplinary and collaborative research in the broad field of Cell & Molecular Biology. The Program produces outstanding graduates with the skills to meet the computational and professional demands of modern life science research. The objectives include to produce more graduates able to apply computational approaches to solve biological problems, provide a robust curriculum for training in this area, encourage and support cross-disciplinary collaborations, and offer training and professional development opportunities to better prepare students for the workforce. The qCMB program is designed to support students engaging in collaborative research projects requiring the generation and analysis of large biological datasets, particularly those generated through sequencing, imaging and flow cytometry. We introduce our early‐stage trainees to coding and its applications through a gateway course led by a supportive group of preceptors and more experienced trainees. As students build confidence, a plethora of elective computational courses support their individual research interests by expanding their quantitative skillsets. Symposia, workshops and group meetings will enhance and support collaboration between program members and between the qCMB program and other campus academic groups. Preceptors will hone their mentoring skills and learn strategies to ensure mentees engage in rigorous, reproducible and responsible research through qCMB resources and trainings. qCMB graduates are prepared to enter the workforce by engaging in career management and leadership training and through opportunities such as internships and guided mentor training. Throughout their PhD studies, qCMB trainees experience a supportive scientific environment that values their contributions, celebrates their successes and guides them through the challenges of graduate school. The effectiveness of training will be demonstrated through evaluations and by following the career trajectories of our graduates. Trainees (6 per year) are selected through a comprehensive process from among the pool of applicants to the CMB program and funded as teaching assistants for the first semester while rotating through preceptor labs. Each will be appointed to fellowship after one semester and will continue with rotations until joining a preceptor lab in Apr/May of the first year. After two years on the award, trainees will be funded through the preceptor's research grant or other fellowship for stipend. The award will support a total of 40 trainees who will then take on positions in academia or industry that require data analysis, collaboration and research experience.

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