AOU WI Area of Interest 1: Community, Participant and Provider Engagement, Enrollment...

Marshfield Clinic Research Foundation, Marshfield WI

Investigators

Linked publications & trials

Abstract

1. ABSTRACT The All of Us Research Program (AoURP) has experienced dramatic change over the last five years. To list just a few of the many examples: AoURP conducted multiple retention eligible campaigns (e.g., mental health campaign), began distributing genetic results to participants, initiated the first ancillary study (Nutrition for Precision Health), and made available the Research Workbench to scientists. Throughout the many changes that have occurred over the years, the most challenging was the SARS-Cov-2 pandemic which disrupted every facet of society and impacted how AoURP's partnering institutions functioned. But with change comes opportunity, and opportunity is possible for organizations that are highly adaptable and innovative. This includes the All of Us Wisconsin Consortium (AoU-WI). AoU-WI was one of the last RMCs to join the national program. As time progressed, AoUWI matured, strengthened close collaborations across WI and nation, and developed diverse strategies in engagement, enrollment, and retention. The diversity at all levels of AoU-WI is something we are most proud of and has allowed our program to flourish in the ever-changing AoURP. To maintain AoU-WI's momentum, we will leverage lessons learned from the last five years. AoU-WI will constantly reassess, modify, and diversify its strategies to ensure AoURP is available to all. Continued diversity in our program will be essential as AoURP persistently changes over the next five years. In this application, we will describe how AoU-WI will not only maintain successful activities that has allowed our program to be leaders in engagement, enrollment, and retention, but how we intend to innovate. We will conduct outreach and engagement activities to promote the enrollment of communities who are historically underrepresented in biomedical research (Aim 1). AoU-WI will also engage, enroll, and retain participants who reflect the rich diversity of the US (Aim 2). This will be done with both adults and pediatrics (Aim3) while ensuring participants have access to technology for study activities (Aim 4). Lastly, AoU-WI will engage and collaborate with health care providers serving communities that are historically underrepresented in biomedical research to facilitate enrollment and retention (Aim5). We will do this by expanding the AoU-WI consortium to include Advocate Aurora Health, the ninth largest not-for-profit integrated healthcare system in the U.S. By successfully achieving these aims, AoU-WI ensures our continuous contribution to the mission of "accelerating health research and medical breakthroughs, enabling individualized prevention, treatment, and care for all of us."