Involvement of Noncanonical Short RNAs in Gene Repression through the RNA-Induced-Silencing Complex

University Of Alabama At Birmingham, Birmingham AL

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Abstract

ABSTRACT: Funded by the parental R01, 5R01GM146756, we have been studying the regulation of a novel family of short RNAs and their functions. These studies require us to prepare carefully size-selected cDNAs that are derived from short RNAs of specific lengths. This proposal is for an equipment supplement that will enable us to purchase a newly available piece of equipment, PippinHT, to more efficiently prepare size-selected cDNA libraries to advance the specific aims of the parental R01.