Mechanism and Inhibition of Protein Methylation

University Of Georgia, Athens GA

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Abstract

We request an administrative supplement to the parent project to acquire an automated flash chromatography system for use in liquid column purification of organic compounds from chemical reaction mixtures. The equipment is important for us to synthesize enzyme inhibitors, chemical probes, optical reporters, and various small molecule and peptide organic compounds to target enzymes and proteins of biomedical significance. Acquiring the equipment will boost the PI’s effort to train next-generation undergraduate students and graduate students in learning modern organic chemistry techniques.