CORE--PATHOLOGY

$0P01FY2002CANIH

Fred Hutchinson Cancer Research Center, Seattle WA

Investigators

Linked publications, trials & patents

Paper 39763516 Paper 39682018 Paper 39606437 Paper 39374522 Paper 39210036 Paper 39169114 Paper 38914227 Paper 38895348 Paper 38828727 Paper 38746248 Paper 38388647 Paper 38380817 Paper 38354704 Paper 37699001 Paper 37655310 Paper 37477588 Paper 37414012 Paper 37394113 Paper 36577856 Paper 36469024 Paper 36369996 Paper 36179985 Paper 36134457 Paper 36088654 Paper 36064752 Paper 36057421 Paper 36030308 Paper 35924583 Paper 35718343 Paper 35584396 Paper 35447514 Paper 35440690 Paper 35292391 Paper 35288345 Paper 35264436 Paper 35235948 Paper 35210305 Paper 35173288 Paper 35138909 Paper 35106927 Paper 35095100 Paper 35007144 Paper 34996099 Paper 34995355 Paper 34741096 Paper 34702753 Paper 34535014 Paper 34269803 Paper 34086185 Paper 34013294 Paper 33914708 Paper 33792629 Paper 33775588 Paper 33750070 Paper 33121238 Paper 33064008 Paper 33002641 Paper 32988787 Paper 32970635 Trial NCT07645469 Trial NCT03970096 Trial NCT03779854 Trial NCT03338972 Trial NCT02770820 Trial NCT02662296 Trial NCT02220985 Trial NCT01858740 Trial NCT01640301 Trial NCT01620229 Trial NCT01527045 Trial NCT01251575 Trial NCT01231412 Trial NCT00968630 Trial NCT00929695 Trial NCT00914940 Trial NCT00702403 Trial NCT00397813 Trial NCT00322101 Trial NCT00118352 Trial NCT00112593 Trial NCT00105001 Trial NCT00104858 Trial NCT00078858 Trial NCT00052598 Trial NCT00052520 Trial NCT00040846 Trial NCT00031655 Trial NCT00027820 Trial NCT00005799 Patent 9987308 Patent 9751928 Patent 9163258 Patent 8014957 Patent 6881557 Patent 6420374 Patent 6040177 Patent 5827642 Patent 5262334 Patent 5225353 Patent 5215927

Abstract

DESCRIPTION (provided by applicant): The anatomic pathology core, a unit dedicated to the Seattle stem cell transplant program, has supported past research with diagnostic and pathogenetic information on graft-versus-host disease (GVHD), infection, toxicity and engraftment. Pathology support for stem cell transplantation has evolved sufficiently to require several technical disciplines for effective functioning. Therefore, we have updated the core to integrate four areas. Anatomic pathology uses standard methods in addition to immunohistochemistry and in situ hybridization on tissue sections to diagnose infection, GVHD, second tumors and chimerism. Molecular cytogenetics uses fluorescent in situ hybridization to recognize chimerism and tumors. Molecular pathology uses PCR methods to detect minimal residual disease. Multiparameter flow cytometry with sorting provides a highly sensitive method for integrating these findings by detecting small numbers of cells with high sensitivity and specificity. These methods provide key support for every aspect of the grant proposal, including every project and most of the core components, both before and long after transplantation.

View original record on NIH RePORTER →