Biostatistics Shared Resource

Albert Einstein College Of Medicine, Bronx NY

Investigators

Linked publications, trials & patents

Abstract

Program Director/Principal Investigator (Last, First, Middle): Chu, Edward BIOSTATISTICS SHARED RESOURCE - PROJECT SUMMARY/ABSTRACT The increasing variety and complexity of data types, analytic approaches and study designs utilized in cancer research necessitate the availability of an organized and centralized biostatistics resource that can offer a wide range of statistical expertise, collaboration, and training opportunities to investigators at the Montefiore Einstein Cancer Center (MECC). The Biostatistics Shared Resource (BSR) is staffed by experienced statisticians with strong track records in effective collaboration across all scientific programs, innovative research in cancer relevant statistical areas, and in training and mentoring investigators at all levels. BSR personnel have critical roles in enhancing the Center infrastructure and fostering multi-disciplinary team science given their broad knowledge of the scope of research activities within the MECC and active involvement on various cancer center committees. The specific objectives of the BSR are: (i) To provide state-of-the-art biostatistical and bioinformatic support on all phases of cancer research, from experimental design and study conduct to data analysis and manuscript preparation; (ii) To collaborate on the development of methodologically rigorous grant applications and new research initiatives; (iii) To assist with the development and scientific review of clinical trial protocols; (iv) To develop innovative biostatistics and bioinformatics approaches to address analytical challenges from new technologies in cancer research; (v) To offer a wide range of biostatistics training opportunities to MECC members and to mentor junior cancer investigators; (vi) To enhance the MECC infrastructure and foster interdisciplinary collaborations via participation on scientific and administrative committees and interactions with other shared resources. In the next funding period, to be in line with the strategic research priorities of the MECC, the BSR will focus on strengthening methodological expertise to address the anticipated needs of existing and newly recruited MECC researchers. Specifically, we have recently established the Subcore of Clinical Trials Methodology focusing on novel clinical trials and pragmatic trials on cancer screening and therapy. In addition, we aim to increase expertise in machine learning approaches that can integrate clinical, laboratory, and different types of high dimensional omics data on cancer etiology, prognosis and precision medicine and prevention and to increase research to address health disparities. The overall goal in accomplishing these objectives is to provide a robust, comprehensive and cost-effective system of statistical support for MECC investigators that contributes significantly to advancing the understanding of cancer etiologies and prognosis, as well as improving cancer prevention, detection and treatment strategies. OMB No. 0925-0001/0002 (Rev. 03/2020 Approved Through 02/28/2023) Page