The Ohio State University Chronic Pancreatitis Diabetes Pancreas Cancer (CPDPC) Clinical Center

$429,103U01FY2024DKNIH

Ohio State University, Columbus OH

Investigators

Philip A. Hartcontact Darwin Lewis Conwell

Linked publications & trials

Paper 39225586 Paper 39137098 Paper 38583544 Paper 38530954 Paper 38518063 Paper 38461145 Paper 38451604 Paper 38423226 Paper 38284831 Paper 38047728 Paper 37530731 Paper 37477620 Paper 37451493 Paper 37436452 Paper 37174299 Paper 37061168 Paper 36535851 Paper 36404274 Paper 36382801 Paper 36191836 Paper 36149018 Paper 35981948 Paper 35881972 Paper 35881699 Paper 35857066 Paper 35721529 Paper 35269531 Paper 35195601 Paper 34571258 Paper 34265796 Paper 34236339 Paper 34172622 Paper 34148967 Paper 34140460 Paper 34089654 Paper 34074860 Paper 34016890 Paper 33558189 Paper 33370019 Paper 32891531 Paper 32595109 Paper 32581043 Paper 32352677 Paper 32285180 Paper 32135127 Paper 31932215 Paper 31764092 Paper 31688587 Paper 31582345 Paper 31232720 Paper 31089778 Paper 30910452 Paper 30908300 Paper 30897605 Paper 30497874 Paper 30325864 Paper 30325863 Paper 30325862 Paper 30325860 Paper 30325859 Paper 30325281 Paper 30268560 Paper 30028444 Paper 29867178 Paper 29859674 Paper 29641209 Paper 29491829 Paper 29456124 Paper 29174078 Paper 28966569 Paper 28919082 Paper 28912670 Paper 28902785 Paper 28824351 Paper 28819564 Paper 28796136 Paper 28741615 Paper 28600657 Paper 28496202 Paper 28476308 Paper 28439020 Paper 28406494 Paper 28404095 Paper 28315036 Paper 28281169 Paper 28268158 Paper 28196021 Paper 28099256 Paper 27837777 Paper 27782962 Paper 27542963 Paper 27481304

Abstract

ABSTRACT The mechanistic underpinnings of diseases involving the exocrine pancreas are poorly understood. Chronic pancreatitis is often accompanied by inflammation of the pancreas, irreversible fibrosis, and destruction of the pancreatic parenchyma resulting in abdominal pain, malnutrition, exocrine pancreatic insufficiency, pancreatogenic diabetes, and, in some cases, pancreas cancer. We have developed a network of adult and pediatric investigators to form The Ohio State University Clinical Center (OSU CC). In a multidisciplinary collaboration with other clinical centers in the Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer Clinical Centers (CPDPC-CCs) (U01), the OSU CC has helped develop four (4) major observational studies during the initial funding cycle to address research gaps in our understanding of diseases of the exocrine pancreas. Specifically, the OSU CC seeks to validate proposed diagnostic biomarkers in chronic pancreatitis, pancreatogenic diabetes, and pancreas cancer.

View original record on NIH RePORTER →