RECOMBINANT IL2 THERAPY OF HIV INFECTED CHILDREN
$0M01FY2002RRNIH
Weill Medical College Of Cornell Univ, New York NY
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Abstract
The central role of Il-2 in enhancing the immune response and the experience of IL-2 therapy in HIV infected adults are the basis for hypothesizing that IL-2 may improve immune function in HIV infected children. Phase I/II dose escalation study where HIV+ asymptomatic children below 18 years will be given daily subcutaneous doses of IL-2 will be conducted. Pharmacokinetics of IL-2 will be evaluated.
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