PREVENTION OF BONE LOSS AND RENAL STONES DURING IMMOBILIZATION

$321,374M01FY2002RRNIH

University Of Texas Sw Med Ctr/Dallas, Dallas TX

Investigators

Linked publications & trials

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Abstract

The goal of this project is to test the hypothesis that osteoclastic bone resorption is inappropriately high in immobilization, and that a third-generation diphosphonate would correct it, thereby averting bone loss and propensity for kidney stone formation. Using the model of bedrest immobilization, the effect of Olapadronate will be compared with that of placebo.

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