VACCINATION AGAINST TUMOR SPECIFIC MUTANT RAS AND P53 PEPTIDES IN CANCER

$321,374M01FY2002RRNIH

University Of Texas Sw Med Ctr/Dallas, Dallas TX

Investigators

Linked publications & trials

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Abstract

This purposes of this study are: 1) to determine whether cellular or humoral immunity specific to an individual patient's tumor mutant ras or p53 oncogene products exists, 2) to determine whether such immunity can be induced or boosted by vacination with a synthetic peptide specific to the mutation in ras or p53 present in a patient's tumor, 3) to assess toxicity from such vaccination, and 4) to determine tumor response following such vaccination.

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