DETERMINATION OF GENOTYPE IN PATIENTS WITH CYSTIC FIBROSIS

$0M01FY2002RRNIH

Children'S Hosp Pittsburgh/Upmc Hlth Sys, Pittsburgh PA

Investigators

Linked publications & trials

Paper 38677871 Paper 38288328 Paper 38278947 Paper 37292813 Paper 34320286 Paper 33479058 Paper 33071178 Paper 32064729 Paper 31685489 Paper 31418516 Paper 31167889 Paper 31118516 Paper 30967435 Paper 30455329 Paper 29936086 Paper 29758564 Paper 29697830 Paper 29427697 Paper 29398050 Paper 29246363 Paper 29157731 Paper 28664624 Paper 28378429 Paper 27803118 Paper 27729426 Paper 27161901 Paper 27129445 Paper 27057209 Paper 27018472 Paper 26628417 Paper 26577415 Paper 26537182 Paper 26531295 Paper 25800542 Paper 25784663 Paper 25702853 Paper 25690268 Paper 24948348 Paper 24552568 Paper 24450390 Paper 24130343 Paper 23974705 Paper 23704677 Paper 23704676 Paper 23704675 Paper 23704674 Paper 23704673 Paper 23704672 Paper 23438494 Paper 23400602 Paper 23340897 Paper 23290511 Paper 23275427 Paper 23275361 Paper 23106941 Paper 22913617 Paper 22912428 Paper 22809659 Paper 22540912 Paper 22489736 Paper 22402864 Paper 22369102 Paper 22332798 Paper 22325254 Paper 22314392 Paper 22293005 Paper 22267104 Paper 22238280 Paper 22146673 Paper 22114879 Paper 21968570 Paper 21933317 Paper 21857919 Paper 21836107 Paper 21796018 Paper 21698649 Paper 21676943 Paper 21674534 Paper 21518410 Paper 21508130 Paper 21466647 Paper 21367931 Paper 21357794 Paper 21325466 Paper 21115769 Paper 20963843 Paper 20962021 Paper 20815724 Paper 20805276 Paper 20592052 Paper 20522169 Paper 20519658 Paper 20416461 Paper 20382696 Paper 20230088 Paper 20189951 Paper 20157322 Paper 20138299 Paper 20067963 Paper 20028940

Abstract

The goal of this study is to determine the genotypes of the patients with cystic fibrosis followed at the Pittsburgh Center so that this information will be available for translational and clinical studies. Over 500 mutations in the CF gene have been described and there are 4 main types of defects which result from these mutations. Since there are different classes of mutations, it can be expected that some drug therapies will be effective only in treatment of mutations of a specific type. In order to benefit the patients, it is necessary to be aware of their genotypes when specific drug therapies become available for use.

View original record on NIH RePORTER →