PATHOLOGIC ALTERATIONS OF THYROID FUNCTION

$0M01FY2002RRNIH

Children'S Hosp Pittsburgh/Upmc Hlth Sys, Pittsburgh PA

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Abstract

Determine etiology and pathogenesis of abnormal thyroid hormone metabolism or secretion in Grave's Disease, Hashimoto's Disease, and congenital hypo- thyroidism. Hormonal homeostasis is assessed during hypo and hyper- thyroidism to determine the role of altered thyroid hormone secretion in metabolic homeostasis.

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