MK0966 vs. nambumetone in osteoarthritis of the knee

$0M01FY2002RRNIH

Case Western Reserve University, Cleveland OH

Investigators

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Abstract

The primary purpose of the study is to compare clinical response rates (excellent or good) of MK-0966 to Nambumetone in the treatment of osteoarthritis of the knee over a 6 week period. The study is designed as a randomized, double-blinded placebo controlled study. Eligible patients will be randomized to one of three treatment groups and will receive either MK-0966 12.5 mg, Nambumetone 10000mg, or placebo, following an NSAIDA washout period. Clinical safety and efficacy data will be collected at 2,4 and 6 weeks of therapy.

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