GERIATRIC DEPRESSION--NEUROBIOLOGY OF TREATMENT

$0M01FY2002RRNIH

University Of Pittsburgh At Pittsburgh, Pittsburgh PA

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Abstract

This study seeks to develop a method for effective rapid treatment of major depressive episodes in the elderly and to improve early identification of treatment non-responders, by combining sleep deprivation (for one night) and paroxetine as probes of treatment response and treatment resistance.

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