FOUR WEEK HIGH DOSE INTERFERON A2B IN STAGE IIA MELANOMA

$0M01FY2002RRNIH

University Of Pittsburgh At Pittsburgh, Pittsburgh PA

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Abstract

This is a Phase II randomized trial of four weeks high dose IFN-a2b in stage IIA melanoma. We propose to study the impact of a single four week course of high dose IFN-a2b given intravenously five-seven days a week. The primary goal of this study is a comparison of observation (Arm A) with high dose IFN-a2b (Arm B) in patients with Stage IA melanoma. The primary endpoints are relapse free survival and overall survival. A secondary endpoint is the assessment of toxicity.

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