Washington National Primate Research Center

University Of Washington, Seattle WA

Investigators

Linked publications & trials

Abstract

ABSTRACT The number of NIH-funded research projects using imaging technology in large animals has been steadily increasing at the University of Washington. One challenge has been the lack of access to 3D x-ray computed tomography. While 2D x-ray radiographs can provide valuable information, there are many use cases in which radiographs provide insufficient information to support funded research studies maximally. The equipment proposed is a Philips Incisive Prox-ray computed tomography (CT) scanner for use in the Animal Research and Care Facility (ARCF) at the University of Washington, under the leadership of the Washington National Primate Research Center (WaNPRC). An important role for the CT scanner is to assist in the placement and monitoring of the position of subdural EEG and other electrodes in the brains of primates as well as the surgical planning for cranial implants, leading to better research outcomes and improved animal welfare. Another need is to use CT imaging to image infection in the lungs to monitor changes and visualize pulmonary infiltrates in long-term studies of maternal-fetal immunology and vaccine/therapeutic studies. Finally, CT imaging capability at the University of Washington will support Veterinary Services by providing more accurate diagnoses and prognoses to guide clinical treatment for nonhuman primates and other large animal models in research projects. The proposed equipment will not only help currently funded research projects but will also accelerate and facilitate novel, future imaging research projects targeted for NIH support.