How bacterial SMC complexes organize chromosomes

Trustees Of Indiana University, Bloomington IN

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Abstract

Project Summary The primary goal of our funded research (1R01GM141242) is to understand how the chromosome is organized and segregated during the cell cycle. We focus on the molecular mechanisms of SMC condensin complex, which is a key player for chromosome dynamics from bacteria to humans. Our projects combine genetic, molecular, cytological, and biochemical approaches. Our research requires a lot of samples to be stored at -80˚C. However, our existing -80˚C is full of essential reagents and we are in need of a new freezer. In this application for Administrative Supplements for Equipment, I am requesting a Cryocube F740HI Freezer, which will allow us to continue to perform the experiments proposed in the parent grant.