Ultrasensitive quantification of cytokine release from T cells

University Of Illinois At Chicago, Chicago IL

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Abstract

PROJECT SUMMARY The limited imaging depth of the current microscopes in the PI’s laboratory poses an obstacle to achieving the overall goal of the parent grant (R35 GM146786). This supplement acquires a single-unit CrestOptics DeepSIM stand-alone system for 3D volumetric superresolution imaging of T cells. The DeepSIM system will substantially expand the experimental capability and accelerate the parent research program.