HIV CO-INFECTIONS IN UGANDAAdministrative Supplement for Research and Capacity Building Efforts Related to Bioethical Issues (Admin Supp Clinical Trial Optional)

$131,943D43FY2023TWNIH

Infectious Diseases Institute, Kampala

Investigators

Andrew Ddungu Kambugucontact Barbara Castelnuovo Yukari C Manabe

Linked publications & trials

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Abstract

Background: Knowledge of research ethics principles and their practical application and ethical theory are not consistently integrated in curriculum requirements in health disciplines training. Research in people living with HIV (PLWH) in resource limited settings (RLS) may pose additionally bioethical challenges for which it is imperative that trainees are exposed to research bioethical training before carrying out research activities Aim. We plan to develop a training program with a blended approach of class training, development of role-plays and case scenarios, and web-based modules to address gaps and equip trainees of the School of Medicine at Makerere University with knowledge in ethics principles in research with PLWH. Specific objectives 1. To understands the training needs in research bioethics for trainees in the area of HIV and co-infections. 2.To develop a short training curriculum comprising class training, including role plays and case scenarios and web-based modules for online training for trainees at the School of Medicine. 3.To pilot and evaluate the developed training, refine and complete the teaching material and content. At the end of the grant this content will be officially handed over to the School of Medicine and the course will be offered annually (post award) as part of the School of medicine training. Methods We plan to conduct a formative phase consisting in a survey of trainees, and in depth interviews, and coordinate the training material with the mentors and the implementation of the training. The findings will guide the development of the training material and content, focusing on complex and understudied populations within PLWH, such as children, adolescents, pregnant and lactating women, elderly people living with HIV, âmost at risk populationâ (e.g. commercial sex workers, sexual minority men, transgender individuals, drug users), and very sick hospitalized patients. We will organize a pilot training course followed by a formal evaluation consisting of a survey and interviews with the trainees. Based on the feedback the training program will be refined and finalized and will be integrated in the teaching modules of the School of Medicine

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