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Mindfulness-Based Stress Reduction: An Implementation Science-Informed Systematic Review and Meta-Analysis

$118,979R01FY2023ATNIH

Brown University, Providence RI

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Abstract

PROJECT SUMMARY: This application seeks a diversity supplement under parent grant, (1R01AT011745-01) which is a comprehensive a systematic review and meta-analysis that seeks to determine the impacts of mindfulness- based stress reduction (MBSR) on key health-related outcomes such as anxiety, depression, stress, physical functioning, quality of life, pain, and cost effectiveness. Compared to other racial and ethnic groups, Black women disproportionately suffer from high rates of hypertension and stress, which are interrelated risk factors for cardiovascular disease (CVD). Physical activity is an important lifestyle modification that is often recommended to treat and prevent hypertension. Mind Body Physical Activity (MBPA) interventions also referred to as ‘mindful exercise’ are uniquely positioned to improve stress management and physical activity outcomes simultaneously. The data on MBPAs in Black populations remains mixed and there is a lack of high-quality systematic reviews and syntheses. This supplement will allow us to expand on the 2nd aim of the parent study: Through a systematic review and meta-analysis, determine the impacts of MBSR on key health-related outcomes informed by the iKT strategy, such as anxiety, depression, stress, physical functioning, quality of life, pain, and cost effectiveness. The proposed supplement is in alignment with the National Center for Complementary and Integrative Health’s strategic objectives to, “foster research on health promotion and restoration, resilience, disease prevention, and symptom management” and to, “advance research on the whole person and on the integration of complementary and conventional care.” This study will provide an opportunity to increase our understanding regarding the efficacy of MBPA interventions for primary and secondary prevention of cardiovascular disease and hypertension risk in a population with high risk and need. To accomplish this goal, we will conduct a mixed-methods systematic review on the effects of MBPA interventions on blood pressure among Black women.

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