Animal cathlab C-arm

Icahn School Of Medicine At Mount Sinai, New York NY

Investigators

Linked publications & trials

Abstract

In this S10 application, we request budget for replacing cathlab system in the Center for Comparative Medicine and Surgery (CCMS) at the Icahn School of Medicine at Mount Sinai (ISMMS). The Cardiovascular Laboratory for Translational Research (CLTR) supported by both Cardiovascular Research Institute and CCMS has been pioneering clinical translation of novel therapeutic approaches. The cathlab system that offered high-throughput, low-mortality experiments in large animals have aged, and C-arm is at end of its equipment life. In order to continue highly active translational cardiovascular research, we propose to replace existing system with state-of-art equipment. The requested items include C-arm and its accessories for cath lab procedures. Despite being smaller than current ceiling-mounted C-arm, image quality will improve significantly due to the technical advances. Moreover, radiation exposure will be substantially reduced and offers safer experiments to investigators and animals. The mobile function also offers imaging during surgery, which was not available in our institution during the past several years. Higher imaging quality will offer improved assessments of cardiovascular morphology and function. The new equipment will lead to improved animal monitoring and reduced measurement variability, which can reduce the number of animals required for each experiment. The new cathlab system will continue to assist translational work of current users, while offering new opportunities to all Mount Sinai investigators with translational interest.