Role of novel VTA neurons in addiction-related behaviors

University Of California, San Diego, La Jolla CA

Investigators

Linked publications, trials & patents

Abstract

PROJECT SUMMARY Thveenttreaglmeanrtea(alVTiAsa)corceomponoeftnhtneeurcailrctuhidatrtriygvoe-asdlirebcetheadvior andaprimtaarrygtehtrowuhgihcdhruogfsabusmeodulbaetheavAilotrh.oguegnherraelglayradsaed dopaminneurcglieacubsoh,uatolfVTAneursoingstnharlorueglheoaftsheaeminaocindeurotransmi GABaAngdlutaTmhaetnsee.uraornaeslstoargoefdtrsuogfasbubsuemtuclhesstudRieecde.envtidence froomulraabndothehrasbsegutnoshotwhalti,VkTeADAneuroancst,iivnViTtAGyABAandglutamat neurcoanpnsrofosuhnadmploeytivbaetheadvFiuortsh.esrumbo-rpeo,puolfVaTtAnieounrsroenlsemaosree thaonneofthetsherreeecycling neurtohncsaot-reldeopaasmeaindelutamoarte, transmitters, including glutaamnaGdtAeBAT.hgeoaolftshpirsopoasrtaeoildenhtoiwtfryanscmiot-trefrlreoaVmsTeAcontribut tothperoceusnsdeesrbleyhianvgrieoirnaflonrtac,nehdmoewco-relneeausrifonungnsctiionntaelgilrnyattoe thmeesolinmebuirccailrctuhiratetsgumloattievbaetheadvWieowriu.lslaenarroafgyeneatpipcroaicnhes combinwaittibhoenhaviaonraatlo,maincdealle,ctrophyassisoailynomsgiictceoaslelectpirvoebtlehye connecatnidfvuintcytoifdoinscVrTeAtceircuits.thicsntinruisnegarch cpormopgrriaasmes Together thoropulgathnodeftihnfeoramnfduncotfnioovncellasosfVeTsAneuraonedsnhanocuuernderstand ofhowintrViTnAhseitcerogsehnaepbieetshyaviorstoneuropsydcihsieaatsrei.c relevant