NEIBank: Est Analysis And Bioinformatics For Ocular Genomics

National Eye Institute

Investigators

Linked publications & trials

Abstract

NEIBank and EyeBrowse (a dedicated genome browser for eye-expressed genes, produced in collaboration with CIT. http://eyebrowse.cit.nih.gov/genome/)consitiute a resource for eye research worldwide. We have developed new informatics tools for functional analysis of RNA-seq data. We combine gene annotations from multiple sources with highly interactive data visualization. This greatly enhances the ease with which important patterns in the data can be discerned. We have applied this approach to expression data for our AMD-related models of retinal pigment epithelium serum starvation. Current efforts are aimed at maintaining the functionality of NEIBank, particularly EyeBrowse for the future.