Design and directed evolution of an 'Edmanase' enzyme for high-throughput peptide sequencing.

Encodia, Inc., San Diego CA

Investigators

Abstract

ABSTRACT More accessible and cost-effective technologies for analysis of the proteome would accelerate biological and medical research. The goal of this proposal is to develop enzymatic reagents to enable creation of a highly-scalable digital protein analysis technology. The approach is broadly applicable and greatly improves upon cost, sensitivity, usability, and throughput of current approaches.