BASE AWARD FOR USING RODENT BEHAVIORAL MODELS TO IDENTIFY SUBSTANCE ABUSE PHARMACOTHERAPIES
$921,200N01FY2019DANIH
University Of North Texas Hlth Sci Ctr, Fort Worth TX
Investigators
Abstract
The purpose of this contract will be to provide testing capacity in the following rodent in vivo assays: mouse locomotor activity, rat drug discrimination, mouse conditioned place preference, and rat self-administration. These models are part of a larger pre-clinical testing hierarchy supported by separate contracts that fund the evaluation of compounds in the rat intracranial self-stimulation assay, various models of relapse to drug-seeking behavior, as well as the primate drug discrimination and self-administration models.
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