NExT NX232-107-158-006 TO#3 Milestone 3 (base) - PK & Bioavail Stud w/Selected Anticancer Compounds in Mice, PK & Pharm Evals of Agents Being Developed for Cancer Patients, HHSN261201600024I/HHSN26100

Mayo Clinic Rochester, Rochester MN

Investigators

Abstract

The purpose of this Task Order is to characterize the plasma pharmacokinetics (PK) and bioavailability of small molecule candidate anticancer compounds in mice in support of NExT project team(s). Rapid turn-around of study results is required. There are nine (9) options for additional studies under this task order. Delivery of a comprehensive spreadsheet (Excel) containing data for all compounds studied is required. This will allow the NExT project team to conduct a comprehensive analysis across compounds.