Structure and Function of Protein C

$374,800R01FY2017HLNIH

Scripps Research Institute, The, La Jolla CA

Investigators

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Abstract

This Administrative Supplement supports studies of the biologic activity of activated protein C (APC), along the lines of this R01 HL052246 project which is focused on the structure-activity relationships of protein C and APC. The Supplement will enable provision of well characterized preparations of wild type, plasma-derived APC for studies of the radioprotective activity of wild type APC in large animals, namely Gottingen minipigs.

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