The Role of Stem Cells and the Microenvironment in Gastrointestinal Cancers
$942,000R35FY2017CANIH
Columbia University Health Sciences, New York NY
Investigators
Linked publications & trials
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Abstract
Summary/Abstract This project seeks to investigate the role of nerves and other stromal cells in the development of digestive cancers, including stomach, esophageal, colon and pancreas. The project builds on previous work that suggests that these elements can regulate stem cells, and that inhibiting stromal cells in the microenvironment, it may be possible to inhibit the development of tumors.
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