Shared Resource: Integrated Microscopy

$101,823P30FY2016CANIH

Baylor College Of Medicine, Houston TX

Investigators

Linked publications & trials

Paper 39713418 Paper 39705355 Paper 39681571 Paper 39668246 Paper 39665756 Paper 39661674 Paper 39653552 Paper 39606477 Paper 39605638 Paper 39605617 Paper 39601621 Paper 39588573 Paper 39580445 Paper 39484515 Paper 39479956 Paper 39477026 Paper 39476839 Paper 39448571 Paper 39432400 Paper 39416207 Paper 39406776 Paper 39404443 Paper 39399665 Paper 39386636 Paper 39372944 Paper 39362577 Paper 39348545 Paper 39345611 Paper 39345554 Paper 39345503 Paper 39339968 Paper 39314272 Paper 39298484 Paper 39287984 Paper 39282295 Paper 39253977 Paper 39225630 Paper 39193992 Paper 39185189 Paper 39149455 Paper 39149310 Paper 39126705 Paper 39125716 Paper 39117669 Paper 39113222 Paper 39093977 Paper 39052788 Paper 39017634 Paper 39009595 Paper 38986621 Paper 38979201 Paper 38953637 Paper 38946944 Paper 38940937 Paper 38906155 Paper 38900051 Paper 38896450 Paper 38885336 Paper 38884472 Paper 38867323 Paper 38834136 Paper 38829671 Paper 38826218 Paper 38824665 Paper 38822527 Paper 38819365 Paper 38816550 Paper 38796854 Paper 38781103 Paper 38773319 Paper 38771986 Paper 38746443 Paper 38739085 Paper 38738472 Paper 38733994 Paper 38729396 Paper 38727682 Paper 38722677 Paper 38716726 Paper 38712292 Paper 38701119 Paper 38662435 Paper 38659962 Paper 38659815 Paper 38658775 Paper 38652491 Paper 38645104 Paper 38641411 Paper 38574731 Paper 38560734 Paper 38560382 Paper 38553595 Paper 38547893 Paper 38538763 Paper 38523431 Paper 38518375 Paper 38516277 Paper 38499995 Paper 38447248 Paper 38438382

Abstract

CORE: Integrated Microscopy Shared Resource (Cell and in vivo Biology Group) PROJECT SUMMARY The Integrated Microscopy Shared Resource (IM SR) provides state-of-the-art-instrumentation, expert consultation, training, and software tools necessary to support cutting-edge cell imaging based research for investigators of the Dan L. Duncan Cancer Center. The instrumentation includes standard brightfield and widefield microscopy, deconvolution and confocal microscopes, high throughput microscopy coupled with automated robotics, and transmission electron microscopy (TEM) with full service processing and sectioning of cells and tissue samples. Plans for near term expansion of technologies and capabilities include scanning electron microscopy (SEM) and super resolution microscopy. The IM SR provides extensive training to DLDCC faculty and their research members to use instrumentation as an unassisted core service. IM SR staff assisted services are also provided to acquire images of user provided samples. An important aspect of both technician assisted and unassisted services is extensive consultation including experimental design, data interpretation, quality control, troubleshooting and assistance and training with commercial and in-house software tools for image analysis. We are also committed to educate cancer center researchers in basic imaging techniques and cutting-edge instruments by way of seminars, hands on workshops, microscopy classes, vendor demonstrations and one-on-one training in immunofluorescence and RNA in situ hybridization using next generation probes. Integrated Microscopy has been a Shared Resource of the DLDCC since its inception in 2006. Since the last renewal of the CCSG, the IM SR has supported the work of ~50 cancer center members annually resulting in ~20 peer-reviewed publications per year. We propose to continue to provide these essential and cutting-edge technologies for the cell imaging research needs of the Cancer Center in the future.

View original record on NIH RePORTER →