SINGLE MOLECULE STUDIES OF OLIGODEOXYRIBONUCLEOTIDES

$155,764P41FY2001RRNIH

University Of Pennsylvania, Philadelphia PA

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Abstract

We have determined the conditions for successful immobilization of oligodeoxy-ribonucleotides on the surface of amino-propyl-silanized glass and mica. We have detected fluorescence images of single 16-mer oligodeoxyribonucleotides labeled by X-rhodamine at the 5'-end and these studies are continuing.

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