SEXUAL DIMORPHISM IN INFLAMMATORY RESPONSE TO BIOMATERIALS: GENDER SPECIFICITY
$0P41FY2001RRNIH
University Of Washington, Seattle WA
Investigators
Linked publications & trials
Paper 25031482Paper 24707067Paper 21974684Paper 18373266Paper 16413313Paper 16413310Paper 16401511Paper 15350787Paper 15318794Paper 15227660Paper 15174104Paper 14741590Paper 14624525Paper 14624512Paper 14517893Paper 14517875Paper 12853263Paper 12834582Paper 12818535Paper 12761836Paper 12747673Paper 12742731Paper 12615480Paper 12547720Paper 12510754Paper 12483694Paper 12361616Paper 12180540Paper 12160301Paper 12160299Paper 12115847Paper 12115464Paper 11985314Paper 11920657Paper 11835157Paper 11787523Paper 11774323Paper 11749152Paper 11587038Paper 11587037Paper 11568141Paper 11526905Paper 11523038Paper 11416844Paper 11334184Paper 11263802Paper 10984706Paper 10919777Paper 10905323Paper 10880115Paper 10813763Paper 10775089Paper 10741670Paper 10737870Paper 10701461Paper 10559740
Abstract
Host cell oxidative responses can alter biomaterials and influence their long-term success. The initial reaction of neutrophils and monocytes with materials may influence the course of the inflammatory response. Previous work in our group has shown that both whole blood and monocytes from females showed a stronger oxidative burst to poly(dimethyl siloxane) PDMS than did whole blood and monocytes from males. The inflammatory response in male and female Balb/c mice to subcutaneous PDMS is being evaluated in an ongoing study. ESCA and SIMS will be used to characterize the PDMS materials.
View original record on NIH RePORTER →