XRAY CRYSTAL STRUCTURE OF AN ARTIFICIAL PROTEIN

$143,176P41FY2001RRNIH

Stanford University, Stanford CA

Investigators

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Abstract

AP1 is a 104 amino acid artificial protein design based on the crystal structure that we determined of a four helix bundle of peptides. If we can solve the X-ray crystal structure it would represent the first artificial protein with a well defined and well determined three dimensional structure; a milestone in the field of de novo design of artificial proteins.

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