CRYSTALLOGRAPHIC STUDIES OF RNA MOTIFS

$143,176P41FY2001RRNIH

Stanford University, Stanford CA

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Abstract

A crystallographically determined structure could give more detailed information on the conformation of the loop nucleotides. A comparison between it and the NMR solution could reveal environment effects. In addition, it will be valuable to build a bank of crystallographically determined RNA structures in order to predict the folding and tertiary structures of larger RNA molecules.

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