Sample Processing and Analysis Core

$270,902P01FY2015CANIH

Brigham And Women'S Hospital, Boston MA

Investigators

Linked publications, trials & patents

Paper 39475509 Paper 39386645 Paper 39321798 Paper 39075252 Paper 38996460 Paper 38905635 Paper 38889153 Paper 38829615 Paper 38819218 Paper 38610997 Paper 38571944 Paper 38538860 Paper 38518098 Paper 38442309 Paper 38394203 Paper 38357791 Paper 38331415 Paper 38271660 Paper 38218188 Paper 38197938 Paper 38167262 Paper 38165043 Paper 38150184 Paper 38096371 Paper 38052038 Paper 38010951 Paper 37931207 Paper 37909388 Paper 37881837 Paper 37873358 Paper 37648862 Paper 37595362 Paper 37591951 Paper 37483562 Paper 37225367 Paper 37197843 Paper 36922589 Paper 36763538 Paper 36455613 Paper 36453519 Paper 36287540 Paper 36264143 Paper 36108743 Paper 35922444 Paper 35853853 Paper 35773251 Paper 35767897 Paper 35763353 Paper 35714308 Paper 35534777 Paper 35512188 Paper 35447071 Paper 35289704 Paper 35245435 Paper 35185150 Paper 35140175 Paper 35015684 Paper 34921959 Paper 34875037 Paper 34855941 Paper 34698806 Paper 34663986 Paper 34614506 Paper 34582559 Paper 34568833 Paper 34551505 Paper 34531254 Paper 34473244 Paper 34465866 Paper 34348451 Paper 34342642 Paper 34027417 Paper 34019641 Paper 33879367 Paper 33872011 Paper 33854168 Paper 33837971 Paper 33753942 Paper 33730585 Paper 33720354 Paper 33690798 Paper 33547048 Paper 33512474 Paper 33408186 Paper 33406418 Paper 33384686 Paper 33371192 Paper 33217342 Paper 33208943 Paper 33015529 Patent 9821068 Patent 9770512 Patent 9750816 Patent 9694084 Patent 8492429 Patent 7858742 Patent 7632660 Patent 7385023 Patent 7112420 Patent 6870040

Abstract

The purpose ofthis core Is to provide a cen tialized laboratory resource for cryopresen/ation and distiibution of patient samples to program investigators. The core virtll also maintain an annotated database with relevant pathologic data for each sample and develop genomic and functional assays to support clinical investigation. This core has 4 Specific Aims: 1. To acquire primary leukemia samples from p atients ente red in clinical research protocols and to isolate and preserve RNA, DNA, and viable mononuclear cells. 2. To maintain an annotated database containing pathologic, cytogenetic and molecular infomiation for clinical samples obtained from patients witii myeloid leukemias. 3. To develop a set of standardized genomic and functional assays to support clinteal investigation. 4. To maintain a bank of AML cell lines optimized for in vivo studies and a bank of AML

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