Mouse Model Core

$235,183P01FY2015HLNIH

University Of Texas Hlth Sci Ctr Houston, Houston TX

Investigators

Linked publications & trials

Paper 38825704 Paper 38688863 Paper 37162892 Paper 35280433 Paper 34600884 Paper 31633303 Paper 30763214 Paper 30661052 Paper 30651002 Paper 30602301 Paper 30322937 Paper 29961567 Paper 29925964 Paper 29689197 Paper 29625025 Paper 29544503 Paper 29494672 Paper 29360940 Paper 29301789 Paper 29300374 Paper 29282246 Paper 29169482 Paper 29038012 Paper 28955046 Paper 28818856 Paper 28652363 Paper 28596165 Paper 28461455 Paper 28099082 Paper 27939641 Paper 27879313 Paper 27879251 Paper 27742556 Paper 27717739 Paper 27580874 Paper 27551047 Paper 26893369 Paper 26854927 Paper 26847850 Paper 26838787 Paper 26837258 Paper 26777256 Paper 26724508 Paper 26621581 Paper 26153420 Paper 25985192 Paper 25936506 Paper 25858068 Paper 25759435 Paper 25557781 Paper 25433566 Paper 25433069 Paper 24951589 Paper 24835173 Paper 24808022 Paper 24786066 Paper 24711452 Paper 24243736 Paper 24082095 Paper 23953976 Paper 23910461 Paper 23897642 Paper 23868934 Paper 23591991 Paper 23580644 Paper 23420843 Paper 23362260 Paper 20683997

Abstract

The UTHSC-Mouse Model Core Laboratory (Core C) will be directed by Dr. Eva M. Zsigmond. Dr. Zsigmond has extensive experience in the generation, identification and breeding of both transgenic and gene-targeted mouse models. The specific aims of the Core C are the following: 1. Generate knock-in mice carrying Acta2 or Myhll mutations. 2. Breed and maintain appropriate lines of these genetically-manipulated mice for various projects within the program. Core C will provide overall colony maintenance and the testing needed for the backcrossing of the colony. 3. Collect, store and make mouse tissues and primary cells available to the other projects. Core C will explant smooth muscle cells from the mouse aortas and provide these primary cultures from the genetically altered mouse models to the PPG investigators.

View original record on NIH RePORTER →