Data Managemet and Statistical Core

$61,826U19FY2015AINIH

Case Western Reserve University, Cleveland OH

Investigators

Linked publications & trials

Paper 38371856 Paper 38307966 Paper 36228920 Paper 36228917 Paper 36099312 Paper 36017364 Paper 34518543 Paper 34449764 Paper 34400687 Paper 33081815 Paper 32985031 Paper 32503607 Paper 32405064 Paper 31492649 Paper 31167926 Paper 30944159 Paper 30922304 Paper 30909928 Paper 30768665 Paper 30541779 Paper 30397622 Paper 29706136 Paper 29665803 Paper 29373596 Paper 29266845 Paper 29141757 Paper 29141726 Paper 29132317 Paper 29029179 Paper 28949293 Paper 28946883 Paper 28862132 Paper 28833064 Paper 28615061 Paper 28222769 Paper 28007921 Paper 27982132 Paper 27821442 Paper 27578850 Paper 27433134 Paper 27348298 Paper 27333893 Paper 27182597 Paper 27131510 Paper 27014875 Paper 26980326 Paper 26969430 Paper 26964528 Paper 26963245 Paper 26960327 Paper 26928594 Paper 26850696 Paper 26842269 Paper 26753618 Paper 26505753 Paper 26440897 Paper 26428458 Paper 26361633 Paper 26259947 Paper 26259946 Paper 26259945 Paper 26259944 Paper 26259943 Paper 26259942 Paper 26259939 Paper 26259938 Paper 26259937 Paper 26237545 Paper 26216993 Paper 26203855 Paper 26149860 Paper 26136391 Paper 26125189 Paper 25996916 Paper 25996619 Paper 25918203 Paper 25883384 Paper 25874894 Paper 25849211 Paper 25734259 Paper 25677924 Paper 25554792 Paper 25547414 Paper 25422270 Paper 25381370 Paper 25341094 Paper 25078358 Paper 24771862 Paper 24440418 Paper 24312682 Paper 24312649 Paper 24040299 Paper 23964936 Paper 23901079 Paper 23405960 Paper 23388506 Paper 23384621 Paper 23379959 Paper 23300556 Paper 22973182

Abstract

The Data Management and Biostatistics Core will build the physical infrastructure, software solutions and human resources for a centralized, web-based fully GCP-compliant data management system and a program-wide data warehouse and provide support for the analyses of complex longitudinal data systems. The Core will serve the data storage and analytic needs of the 3 Research Projects conducted in all malaria endemic sites ofthe ICEMR and interact directly with the Molecular Diagnostics Core that will create an archive of biological samples and perform diagnostic tests related to malaria infections of humans and mosquitoes. The Specific Aims are to: 1: Set up a robust and comprehensive, centralized, web-based fully GCP-compliant data management system for ICEMR program 2; Create a collaborative environment between Papua New Guinea and participating sites in Solomon Islands and other ICEMR institutions and countries for the design, development, testing, and implementation of the data management system 3: Establish a centralized data repository that provides secure access to researchers and collaborators 4: Develop adequate data analysis tools for the analyses of complex longitudinal datasets (with multiple endpoints) 5: Analyze data and prepare results in a timely manner for interim analyses, publications, and presentations 6; Ensure regulatory compliance of data collection management 7: Provide training and development opportunities to Papua New Guinea and Solomon Islands in the areas of epidemiology, biostatistics, and database architecture The core will be directed by Prof. John Aponte from CRESIB, where he has organized similar data systems for large scale malaria epidemiology studies and clinical trials in Sub-Saharan Africa, and supported by Dr. Ivo Mueller, leader ofthe Epidemiology Project, and Thomas Adiguma, senior data manager at PNGIMR. Infrastructure and capacity building will be accomplished by the provision of training and resources in the fields of epidemiology, biostatistics, and dataset architecture.

View original record on NIH RePORTER →