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Development of a normative database for wide-band acoustic immittance measures

$334,817R15FY2014DCNIH

Smith College, Northampton MA

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Abstract

DESCRIPTION (provided by applicant): This work aims to develop wideband acoustic immittance (WAI) measures as a noninvasive auditory diagnostic tool, where WAI refers to the collection of both power-based and impedance-based measurements that include absorbance, power reflectance, impedance, and related quantities. Potential use of these measures includes (1) detection of fluid in newborn and young infant ears where tympanometry is less successful, (2) identification of the cause of a conductive hearing loss (e.g., fluid, disarticulated ossicle, fixed ossicle), and (3) monitoring changes in middle-ear stiffness that result from intracranial pressure changes. The work proposed here continues and formalizes the development of a normative database for WAI measures, which to date has been largely ad hoc. In particular, a database is proposed that will initially be populated with data collected from the proposed work and ultimately include procedures to allow for contributions of data from other researchers. The proposed work includes measurements on human subjects that are designed to determine how normative WAI measures depend on the parameters: instrumentation, age, gender, and race. The results will determine whether or not normative data would need to be parameterized for any of these quantities. A second emphasis of the proposed work is the research-based education of undergraduate students at Smith College, an all-women's liberal arts college. Undergraduate engineering students will be actively involved in all areas of the proposed work, with the goal of encouraging them to consider continuing their education toward a Ph.D.

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