TAXOL IN PATIENTS W/ ADVANCED NON SMALL CELL LUNG CANCER

$0M01FY2001RRNIH

Vanderbilt University, Nashville TN

Investigators

Linked publications & trials

Paper 33558372 Paper 32454300 Paper 29993499 Paper 28369419 Paper 28194433 Paper 27832858 Paper 27718206 Paper 27498869 Paper 26967998 Paper 26908300 Paper 26677460 Paper 26637290 Paper 26411798 Paper 26125411 Paper 26120597 Paper 26055866 Paper 26009829 Paper 25990642 Paper 25936660 Paper 25884888 Paper 25869442 Paper 25820827 Paper 25765720 Paper 25734077 Paper 25660347 Paper 25641887 Paper 25261246 Paper 25232828 Paper 25118837 Paper 25117929 Paper 25026915 Paper 24939976 Paper 24768120 Paper 24752680 Paper 24699314 Paper 24637543 Paper 24384588 Paper 24349219 Paper 24290979 Paper 24284293 Paper 24121755 Paper 24037626 Paper 23972786 Paper 23956809 Paper 23884469 Paper 23863960 Paper 23863228 Paper 23799953 Paper 23786504 Paper 23630356 Paper 23600543 Paper 23592367 Paper 23557458 Paper 23543059 Paper 23523131 Paper 23503447 Paper 23502781 Paper 23385328 Paper 23337848 Paper 23288871 Paper 23279924 Paper 23241069 Paper 23229731 Paper 23204253 Paper 23195626 Paper 23106931 Paper 23106930 Paper 23106929 Paper 23106928 Paper 23106927 Paper 23106926 Paper 23106925 Paper 23106924 Paper 23106923 Paper 23073617 Paper 23040286 Paper 22760537 Paper 22723323 Paper 22721633 Paper 22648267 Paper 22570963 Paper 22552860 Paper 22537984 Paper 22435735 Paper 22360812 Paper 22354163 Paper 22287587 Paper 22198906 Paper 22160300 Paper 22088886 Paper 21964369 Paper 21858673 Paper 21716327 Paper 21633409 Paper 21605660 Paper 21572029 Paper 21533241 Paper 21490026 Paper 21420789 Paper 21420510

Abstract

SPI-77 and paclitaxel can be safely administered as a drug combination in patients with non-small cell lung cancer previously treated with chemotherapy. A maximally tolerated dose can be established which will characterize the toxicities of SPI-77 plus paclitaxel in patients with advanced non-small cell lung cancer, and determine the maximum tolerated dose of SPI-77 when given in combination with a fixed dose of paclitaxel administered every 3 weeks. Determine also the pharmacokinetics of SPI-77 and paclitaxel at the MTD, and assess any responses that may result from the combination treatment of SPI-77 and paclitaxel.

View original record on NIH RePORTER →