CYSTEINE &GLUTATHIONE METABOLISM IN HEALTHY SUBJECTS
$0M01FY2001RRNIH
Massachusetts Institute Of Technology, Cambridge MA
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Paper 20400410Paper 18657126Paper 18280316Paper 18278630Paper 18025896Paper 17636096Paper 16158084Paper 15883435Paper 15545977Paper 15531674Paper 15240605Paper 15138154Paper 15044663Paper 14647179Paper 14647177Paper 14634685Paper 14625206Paper 12936932Paper 12917718Paper 12730432Paper 12399276Paper 12045492Paper 11821342Paper 11600532Paper 11114177Paper 10974208Patent 6579899Patent 5595772Patent 5223540Patent 5179126Patent 4999382Patent 4971998Patent 4649161Patent 4626527
Abstract
A pilot study aimed to determine basic aspects of cysteine and glutathione metabolism under conditions of a sulfur free amino acid diet. Cysteine availability is the rate limiting step in glutathione synthesis. We hypothesized that during a short term sulfur-free amino acid diet the rates of Glutathione synthesis are maintained at the expense of increased protein turnover.
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