ANTIB1 ANTIBODY FOR B CELL CHRONIC LYMPHOCYTIC LEUKEMIA

$0M01FY2001RRNIH

Stanford University, Stanford CA

Investigators

Linked publications & trials

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Abstract

This study involves the use of a radioisotope(I131) targeted to tumor cells in patients with refractory chronic lymphocytic leukemia. We wish to determine the maximum tolerated dose of Idodine-131 Anti-B1 Antibody in patients with platelet counts>100,000 cells/mm3(Cohort A) and in patients with platelet counts from 75,000-100,000 cells/mm3(Cohort B) with previously treated intermediate or high-risk B-cell CLL. Also we would like to determine the safety and efficacy of Iodine-131 Anti-B1 Antibody in patients with previously treated intermediate or high-risk B-cell CLL.

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