Tumor pyruvate kinase as key regulator of cancer metabolism
$234,059R00FY2013CANIH
University Of California, Merced, Merced CA
Investigators
Linked publications & trials
Paper 36993709Paper 36911273Paper 33594203Paper 32151278Paper 31871830Paper 31706703Paper 31611594Paper 31118427Paper 30792348Paper 30281213Paper 30281145Paper 29977600Paper 29615030Paper 29052507Paper 28852500Paper 28757815Paper 28416760Paper 28405267Paper 28369194Paper 28265786Paper 27623747Paper 27063195Paper 26936398Paper 26609109Paper 26304929Paper 26055627Paper 25600636Paper 24527465Paper 23961261Paper 22846158Paper 22360810Paper 21998308Paper 18157808Paper 18024138Paper 17566986Paper 17157249Paper 15243180Paper 12453410
Abstract
The project seeks to understand the role of pyruvate kinase as regulator of cancer metabolism. Insight into glycolytic and TCA cycle flux from metabolic profiles of cancer cell lines will reveal new drug targets and generate new regimes for diagnosis and treatment of cancer patients.
View original record on NIH RePORTER →