DENDRITIC CELL THERAPY FOR PROSTATE CANCER

$0M01FY2001RRNIH

Stanford University, Stanford CA

Investigators

Linked publications & trials

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Abstract

Prostatic Acid Phosphatase is a prostate-specific antigen expressed by both normal and malignant prostate tissue. To explore the potential role of xenoantigen immunization in prostate cancer, we initiated a phase I/IIa trial using dendritic cells (DC) pulsed with recombinant mouse PAP as a tumor vaccine. Eligible patients had recurrent prostate cancer, rising serum PSA, and no recent or concurrent changes in therapy.

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