Systemic Nanocurcumin for Pancreatic Cancer Therapy

$284,683U54FY2013CANIH

Johns Hopkins University, Baltimore MD

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Abstract

Curcumin, a yellow polyphenol compound found in the Indian spice turmeric (Curcuma longa) demonstrates potent anti-cancer effects against a wide variety of human tumor models in preclinical studies. A major pitfall forthe application of curcumin to human cancer therapy has been its limited systemic bioavailability, such that the few clinical trials conducted so far had administered

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